DENDRIMERS FOR DRUG DELIVERY

Dendrimers for Drug Delivery

Dendrimers have come a long way in the last 25 years since their inception.Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers.Dr.Donald Tomalia first published his seminal work on Poly(amidoamine) (PAMAM) dendrimers in 1985.Application of dendrimers as a drug delivery system started in late 1990s.

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Kawasaki Disease-like Vasculitis Facilitates Atherosclerosis, and Statin Shows a Significant Antiatherosclerosis and Anti-Inflammatory Effect in a Kawasaki Disease Model Mouse

Kawasaki disease (KD) is an acute form of systemic vasculitis that may promote atherosclerosis in adulthood.This study examined the relationships between KD, atherosclerosis, and the long-term effects of HMG-CoA inhibitors (statins).Candida albicans water-soluble fraction (CAWS) was injected intraperitoneally into 5-week-old male apolipoprotein-E-d

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A Rare Case of Castleman Variant of POEMS Syndrome

POEMS syndrome is a rare multisystemic disease, characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes.The presence of polyneuropathy and monoclonal plasma cell proliferation is mandatory for the diagnosis of typical POEMS syndrome.However, some patients lack one of the mandatory features and are classif

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